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Objectives: To evaluate the in vitro cytotoxic effects of hydrogen peroxide (H2O2) on periodontal cells, based on the cellular viability and morphology of immortalized osteoblast and gingival fibroblast cultures, with different exposure times and concentrations. Methods: Immortalized human gingival fibroblast and hu...

In vitro cytotoxicity testing of dental acrylic resins is fundamental to establish clinical safety limits, requiring suitable cell models that closely simulate physiological processes. This study’s main aim is to evaluate the viability of an untransformed human gingival fibroblast cell line, as an oral cell mo...