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Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial

SPEMD - Revista Portuguesa de Estomatologia Medicina Dentária e Cirurgia Maxilofacial | 2023 | 64 (3) | Page(s) 128-132


Clinical case

Management of pediatric erythema multiforme restricted to the mouth and perioral region: A case report

Tratamento de eritema multiforme pediátrico restrito à boca e região perioral: Caso clínico


a Post-Graduation Program in Dentistry, Department of Dental Clinic, Division of Oral Pathology, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará (UFC), Fortaleza, Brazil
b Faculty of Dentistry, Federal University of Ceará Campus Sobral (UFC), Sobral, Brazil
c Dentistry Course, Christus University Center (Unichristus), Fortaleza, CE, Brazil
d Department of Morphology, School Medicine, Federal University of Ceará (UFC), Fortaleza, Brazil
Pedro Henrique Chaves Isaias - ph.isaias@yahoo.com.br

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Volume - 64
Issue - 3
Clinical case
Pages - 128-132
Go to Volume


Received on 23/04/2023
Accepted on 25/08/2023
Available Online on 27/09/2023


Erythema multiforme is a mucocutaneous disease characterized by the acute appearance of blisters and ulcers, with or without oral involvement. In this report, a 12-year-old female patient presented with extensive ulcerative lesions on the upper and lower lips, with painful symptoms and areas of bleeding and suppuration. Despite these lesions being restricted to the lips and skin around, the patient was diagnosed with erythema multiforme. Dexamethasone was then prescribed, in addition to the use of lip balm. At the first return evaluation, there was no regression of the clinical picture, and the medication was replaced by prednisone, associated with amoxicillin and 0.12% chlorhexidine mouthwash. In the second return visit, there was considerable regression of the lesion, and the process of gradual discontinuation of the corticosteroid was initiated. After 1 week, the lesions had healed, and the drug was discontinued. The oral cavity may be the only site affected by erythema multiforme, so knowledge of this disease is necessary for its correct diagnosis and treatment.


O eritema multiforme é uma doença mucocutânea, caracterizada pela ocorrência súbita de bolhas e úlceras, com ou sem envolvimento da cavidade oral. No presente relato, uma paciente do sexo feminino, com 12 anos de idade, apresentou lesões ulceradas extensas nos lábios, superior e inferior, acompanhadas de sintomas dolorosos, zonas de hemorragia e supuração. Embora essas lesões estivessem localizadas apenas nos lábios e na pele circundante, a paciente recebeu o diagnóstico de eritema multiforme. Foi então prescrita dexametasona, juntamente com a indicação de protetor labial. Na primeira avaliação de retorno, não houve regressão do estado clínico, resultando na substituição do medicamento por prednisona, em combinação com amoxicilina e colutório de clorexidina a 0,12%. Na segunda consulta de acompanhamento, houve regressão considerável da lesão, iniciando-se, assim, o processo gradual de suspensão do corticosteroide. Após 1 semana, as lesões cicatrizaram e o medicamento foi interrompido. A cavidade oral pode ser o único local afetado pelo eritema multiforme, sendo necessário o conhecimento dessa doença para o seu correto diagnóstico e tratamento.


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